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. 2022 Sep 6;13:981604. doi: 10.3389/fphar.2022.981604

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Copyright © 2022 Guo, Zhou, Lin, Li, Tan and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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WGCNA analysis and the functional pathway analysis. (A) The results of the DEGs of COVID-19. (B,C) Network topology analysis of different soft threshold power. (D) Dendrograms of genes acquired by mean linkage hierarchical clustering, A color branch of the cluster tree represents a co-expression module. (E) Module-trait relationships. The red color represents positive correlation and the green color represents negative correlation. The significance of the correlation was indicated by p-value. (F) The correlation between blue module and COVID-19. (G,H) The results of GO and KEGG pathway enrichment analysis.