Table 2.

Fatigue measured at baseline and after 14 days of following a 10-hour time-restricted eating pattern (n=36).

Fatigue measure	Directionality	Baseline	Day 14	p-value*	Effect size
Functional Assessment of Chronic Illness Therapy- Fatigue (FACIT-F) Total score	Higher is better	107.9 ± 17.3	117.2 ± 19.6	<0.001**	0.50
FACIT-F: Physical well being	Higher is better	19.9 ± 4.1	21.4 ± 4.7	0.006**	0.32
FACIT-F: Social well being	Higher is better	22.8 ± 5.7	23.1 ± 5.5	0.529	0.06
FACIT-F: Emotional well being	Higher is better	18.5 ± 3.7	19.1 ± 3.5	0.144	0.18
FACIT-F: Functional well being	Higher is better	16.0 ± 4.5	17.3 ± 4.9	0.005**	0.35
FACIT-F: Fatigue subscale	Higher is better	30.6 ± 9.2	35.9 ± 9.9	<0.001**	0.55
FACIT-F: Trial outcome index (fatigue)†	Higher is better	66.6 ± 14.8	74.9 ± 17.3	<0.001**	0.52
FACIT-F: Functional Assessment of Cancer Therapy (FACT)-General‡	Higher is better	77.2 ± 12.3	81.3 ± 13.0	0.001**	0.32
Brief Fatigue Inventory: Global fatigue score	Lower is better	3.9 ± 1.6	2.9 ± 1.9	0.001**	−0.58
Brief Fatigue Inventory: Fatigue at its worst	Lower is better	6.8 ± 1.9	5.2 ± 2.6	<0.001	−0.69
Symptom inventory: Fatigue	Lower is better	5.8 ± 2.4	4.4 ± 2.3	0.002**	−0.62
Symptom inventory: Sleep problems	Lower is better	4.7 ± 2.9	4.2 ± 3.0	0.374	−0.18
Symptom inventory: Drowsiness	Lower is better	5.2 ± 2.5	3.0 ± 2.3	<0.001**	−0.89
Symptom inventory: Interference of symptoms with quality of life	Lower is better	4.0 ± 2.9	2.3 ± 2.6	0.001**	−0.62

^*p-value derived from a two-sided, paired t-test between baseline and Day 14

^**p<0.01

^†Trial outcome index (fatigue) = physical + functional + fatigue subscales

^‡Functional Assessment of Cancer Therapy (FACT)-General = physical + social + emotional + functional subscales; a common measure of quality of life