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. 2022 Jan 26;31(163):210150. doi: 10.1183/16000617.0150-2021

TABLE 1.

Wide-ranging clinical manifestations of hypereosinophilic syndromes [43, 44]

General
Fatigue, myalgia, weight loss, fever
Ocular
Retinal micro-emboli, choroidal inflammation
Pulmonary
Asthma, lung infiltrates, fibrosis
Splenic
Splenomegaly
Gastrointestinal
(Gastro-)enteritis, colitis
Sino-nasal cavities
Chronic rhinosinusitis, polyposis
Hepatic
Hepatitis, cholangitis
Soft tissue/rheumatologic
Angioedema, fasciitis, myositis, synovitis, arthritis
Neurologic
Embolic stroke, encephalitis, peripheral neuropathy
Dermatologic
Pruritis, eczema, dermatitis, urticaria, erythroderma
Vascular
Arterial/venous thrombosis, microvascular damage, vasculitis
Cardiac
Myocarditis, intracavitary thrombus, subendocardial fibrosis, valve entrapment, pericarditis