TABLE 2.

Different phenotypes of Pseudomonas aeruginosa in the cystic fibrosis lung

Phenotype	Description	Reference
Small colony variants	Slow-growing High antibiotic resistance	[150]
Mucoid variants	Alginate overproduction	[151]
Auxotrophic variants	Dependent on specific amino acids for growth	[46]
Hypermutable variants	Very likely to develop multidrug resistance	[152]
LasR deficient variants	Lower virulence: lower pyocyanin production, lower production of LasA protease, less efficient biofilm initiation	[153]
Type III secretion system deficient variants	Deficient ExoU (effector protein) secretion: lower cytotoxicity and lower virulence	[154]
Pyomelanine producing variants	Pyomelanine hyperproduction Increased antibiotic resistance	[155]