Table 2: Univariate analyses of melatonin association with IL-1B .
Variables | Coefficient | Std. Err | t | P value | 95% CI |
Sex (Female) | -326 | 572.87 | -0.60 | 0.50 | -1403.73, 751.72 |
Age | 21.47 | 23.81 | 0.90 | 0.37 | -25.83, 68.78 |
BMI | 6.50 | 7.22 | 0.90 | 0.30 | -7.85, 20.84 |
Total cholesterol (mg/dL) | 1.30 | 5.64 | 0.24 | 0.81 | -9.89, 12.55 |
LDL (mg/dL) | -1.73 | 9.14 | -0.20 | 0.85 | -19.90, 16.48 |
HDL (mg/dL) | 32.03 | 34.04 | 0.94 | 0.35 | -35.74, 99.80 |
Triglyceride (mg/dL) | 2.48 | 3.32 | 0.75 | 0.45 | -4.12, 9.10 |
AST (U/L) | 24.59 | 8.20 | 3.00 | 0.003 | 8.31, 40.86 |
ALT (U/L) | 21.52 | 6.03 | 3.54 | 0.001 | 9.45, 33.59 |
Alkaline phosphatase (U/L) | 5.32 | 4.28 | 1.24 | 0.20 | -3.17, 13.83 |
FBS | 16.42 | 8.90 | 1.85 | 0.060 | -1.30, 34.17 |
Stages of fibrosis | |||||
Mild to moderate | 374 | 617.10 | 0.61 | 0.05 | -851.28, 1599.28 |
Severe | 1683.17 | 623.90 | 2.70 | 0.006 | 444.35, 2921.99 |
Stages of steatosis | |||||
Mild to moderate | -20.58 | 721.72 | -0.03 | 0.977 | -1453.59, 1412.43 |
Severe | 1472.96 | 594.78 | 2.48 | 0.015 | 292.01, 2653.91 |
Melatonin | 3.45 | 0.40 | 8.53 | < 0.001 | 2.64, 4.25 |
BMI: body mass index; AST: Aspartate transaminase; ALT: Alanine aminotransferase; ALP: Alkaline phosphatase; FBS: Fasting blood sugar