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. 2022 Jan 30;14(1):110–117. doi: 10.34172/mejdd.2022.263

Table 2: Univariate analyses of melatonin association with IL-1B .

Variables Coefficient Std. Err t P value 95% CI
Sex (Female) -326 572.87 -0.60 0.50 -1403.73, 751.72
Age 21.47 23.81 0.90 0.37 -25.83, 68.78
BMI 6.50 7.22 0.90 0.30 -7.85, 20.84
Total cholesterol (mg/dL) 1.30 5.64 0.24 0.81 -9.89, 12.55
LDL (mg/dL) -1.73 9.14 -0.20 0.85 -19.90, 16.48
HDL (mg/dL) 32.03 34.04 0.94 0.35 -35.74, 99.80
Triglyceride (mg/dL) 2.48 3.32 0.75 0.45 -4.12, 9.10
AST (U/L) 24.59 8.20 3.00 0.003 8.31, 40.86
ALT (U/L) 21.52 6.03 3.54 0.001 9.45, 33.59
Alkaline phosphatase (U/L) 5.32 4.28 1.24 0.20 -3.17, 13.83
FBS 16.42 8.90 1.85 0.060 -1.30, 34.17
Stages of fibrosis
Mild to moderate 374 617.10 0.61 0.05 -851.28, 1599.28
Severe 1683.17 623.90 2.70 0.006 444.35, 2921.99
Stages of steatosis
Mild to moderate -20.58 721.72 -0.03 0.977 -1453.59, 1412.43
Severe 1472.96 594.78 2.48 0.015 292.01, 2653.91
Melatonin 3.45 0.40 8.53  < 0.001 2.64, 4.25

BMI: body mass index; AST: Aspartate transaminase; ALT: Alanine aminotransferase; ALP: Alkaline phosphatase; FBS: Fasting blood sugar