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. 2022 Jan 30;14(1):110–117. doi: 10.34172/mejdd.2022.263

Table 3: Univariate analyses of melatonin association with IL-18 .

Variables Coefficient Std. Err t P value 95% CI
Sex (Female) 7.07 4.53 1.56 0.12 -1.90, 16.06
Age 0.38 0.192 2.0 0.04 0.00, 0.76
BMI 0.07 0.06 1.29 0.20 -0.04,0.20
Total cholesterol (mg/dL) 0.04 0.04 0.98 0.33 -0.04, 0.13
LDL (mg/dL) -0.03 0.07 -0.46 0.63 -0.18,0.11
HDL(mg/dL) 0.11 0.27 0.40 0.60 -0.44, 0.66
Triglyceride(mg/dL) 0.05 0.02 2.15 0.03 0.00, 0.10
AST (U/L) 0.26 0.06 3.90  < 0.001 0.13, 0.39
ALT (U/L) 0.18 0.05 3.64  < 0.001 0.08, 0.28
ALP (U/L) 0.05 0.03 1.55 0.12 -0.01, 0.12
FBS 0.10 0.07 1.49 0.14 -0.03, 0.25
Stages of fibrosis
Mild to moderate 14.61 5.14 2.84 0.006 4.38, 24.83
Severe 12.05 5.20 2.32 0.02 1.71, 22.40
Stages of steatosis
Mild to moderate 2.46 6.14 0.40 0.689 -9.73, 14.65
Severe 12.13 5.06 2.40 0.018 2.09, 22.18
Melatonin 0.02 0.00 5.85  < 0.001 0.01, 0.03

BMI:body mass index; AST: Aspartate transaminase; ALT: Alanine aminotransferase; ALP: Alkaline phosphatase; FBS: Fasting blood sugar