Table 3: Univariate analyses of melatonin association with IL-18 .
Variables | Coefficient | Std. Err | t | P value | 95% CI |
Sex (Female) | 7.07 | 4.53 | 1.56 | 0.12 | -1.90, 16.06 |
Age | 0.38 | 0.192 | 2.0 | 0.04 | 0.00, 0.76 |
BMI | 0.07 | 0.06 | 1.29 | 0.20 | -0.04,0.20 |
Total cholesterol (mg/dL) | 0.04 | 0.04 | 0.98 | 0.33 | -0.04, 0.13 |
LDL (mg/dL) | -0.03 | 0.07 | -0.46 | 0.63 | -0.18,0.11 |
HDL(mg/dL) | 0.11 | 0.27 | 0.40 | 0.60 | -0.44, 0.66 |
Triglyceride(mg/dL) | 0.05 | 0.02 | 2.15 | 0.03 | 0.00, 0.10 |
AST (U/L) | 0.26 | 0.06 | 3.90 | < 0.001 | 0.13, 0.39 |
ALT (U/L) | 0.18 | 0.05 | 3.64 | < 0.001 | 0.08, 0.28 |
ALP (U/L) | 0.05 | 0.03 | 1.55 | 0.12 | -0.01, 0.12 |
FBS | 0.10 | 0.07 | 1.49 | 0.14 | -0.03, 0.25 |
Stages of fibrosis | |||||
Mild to moderate | 14.61 | 5.14 | 2.84 | 0.006 | 4.38, 24.83 |
Severe | 12.05 | 5.20 | 2.32 | 0.02 | 1.71, 22.40 |
Stages of steatosis | |||||
Mild to moderate | 2.46 | 6.14 | 0.40 | 0.689 | -9.73, 14.65 |
Severe | 12.13 | 5.06 | 2.40 | 0.018 | 2.09, 22.18 |
Melatonin | 0.02 | 0.00 | 5.85 | < 0.001 | 0.01, 0.03 |
BMI:body mass index; AST: Aspartate transaminase; ALT: Alanine aminotransferase; ALP: Alkaline phosphatase; FBS: Fasting blood sugar