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Effects of EGCG combined with irinotecan on the growth of subcutaneous colorectal tumor in balb/c nude mice. Changes in body weight (a) and tumor volume (b, c) of HCT116 cell xenograft mice treated with EGCG and/or irinotecan. (d) The expression of Ki67, GRP78, and cleaved-caspase3 was detected by IHC after taking out the mouse tumor. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.005. #P < 0.05, ##P < 0.01.
