Fig. 1.

Locomotor activity rhythm and Per1 gene expression of Per1-luc mice in UV LD conditions.

(A). Locomotor activity rhythm under UV 12/12 light-dark conditions. Spontaneous locomotor activity records are expressed in black histograms of activity counts in 5 min bin and double-plotted so that 48 h are shown on the x-axis and consecutive days on the y-axis. (B). The effect of UV light on behavior rhythm in subjective day and night. Grey squares show the time zone when the UV light pulse was exposed (CT13-16 or CT8-11). Red lines show the regression lines fitted to the onset of activity time before and after UV light exposure. (C). The effect of UV light on locomotor activity rhythm by 3h UV light exposure in DD conditions. Each column indicates the mean ± SD (n = 3). Statistical significance was detected by Student’ t-test (***P < 0.05 vs. CT8∼11). (D, E).Per1 expression rhythm in the liver of Per1-luc mouse in UV LD conditions (D) and DD conditions (E). Luminescence (red curve) was computed by subtracting the 24 h moving average from the original data. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)