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. Author manuscript; available in PMC: 2023 Oct 1.
Published in final edited form as: Ann Neurol. 2022 Aug 3;92(4):663–669. doi: 10.1002/ana.26443

Table 1.C.

Predictors of PTS Recurrence. We report predictors of PTS recurrence (i.e., a second PTS). Although the likelihood of PTS recurrence varies by follow-up time, the effect is minimal and explored in Supplementary Table 2. Time zero is the time of the first late PTS. For p-values, we used 2-sided t-tests for normally distributed continuous variables and a chi-squared or Fisher’s exact test for categorical variables.

Description No PTS Recurrence
(n=26)
PTS Recurrence
(n=72)
p-value
Demographic Age 36 +/− 16 30 +/− 12 0.07
Race American Indian 1/26 (4%) 0/72 (0%) 0.39
Asian/Indian 0/26 (0%) 0/72 (0%)
Black 1/26 (4%) 2/72 (3%)
White 24/26 (92%) 70/72 (97%)
Other 0/26 (0%) 0/72 (0%)
Sex (male) 18/26 (69%) 62/72 (86%) 0.08
Clinical GCS 3 5/26 (19%) 8/72 (11%) 0.35
4 2/26 (8%) 5/72 (7%)
5 3/26 (11%) 3/72 (4%)
6 7/26 (27%) 16/72 (22%)
7 9/26 (35%) 35/72 (49%)
8 0/26 (0%) 5/72 (7%)
Hypoxia 5/25 (20%) 7/67 (10%) 0.30
Hypotension 6/26 (23%) 11/67 (16%) 0.55
Major extracranial injury 3/26 (12%) 6/67 (9%) 0.71
EVD hemorrhage 3/25 (12%) 8/71 (11%) 0.99
CNS Infection 5/26 (19%) 14/72 (19%) 0.98
DHC 11/26 (42%) 44/72 (61%) 0.10
Craniotomy 15/26 (58%) 50/72 (69%) 0.28
Shunt 10/26 (38%) 20/72 (28%) 0.31
Lobectomy 3/26 (12%) 14/72 (19%) 0.55
LOS 29 +/− 13 27 +/− 13 0.59
ICU LOS 23 +/− 9 21 +/− 10 0.33
Laboratory Glucose 136 +/− 40 165 +/− 65 0.01
Hemoglobin 13.0 +/− 1.8 13.5 +/− 1.8 0.27
INR 1.2 +/− 0.3 1.2 +/− 0.2 0.60
Intoxicated 13/20 (65%) 25/56 (45%) 0.12
Radiographic SDH 14/26 (54%) 36/70 (51%) 0.83
EDH 4/25 (16%) 9/68 (13%) 0.74
tSAH 19/25 (76%) 53/68 (78%) 0.84
IVH 5/25 (20%) 15/70 (21%) 0.88
Contusion 16/26 (62%) 45/70 (64%) 0.80
Depressed Skull Fracture 7/26 (27%) 16/70 (23%) 0.68
Petechial hemorrhage 14/23 (61%) 44/64 (69%) 0.49
Obliteration of the 3rd ventricle 7/23 (30%) 20/64 (31%) 0.94
Midline Shift 9/26 (35%) 31/70 (44%) 0.45
MLS > 5mm 6/26 (23%) 22/70 (31%) 0.42
Marshall CT score 1 1/25 (4%) 0/68 (0%) 0.36
2 12/25 (48%) 33/68 (49%)
3 1/25 (4%) 9/68 (13%
4 3/25 (12%) 5/68 (7%)
5 8/25 (32%) 21/68 (31%)
6 0/25 (0%) 0/68 (0%)