Table 2.

Sensitivity, specificity, and predictive values for antemortem and postmortem CSF αSyn-SAA against αSyn-pathology.

ANTEMORTEM (n=119)
Variable	Value, % (95% CI)
Sensitivity	71.2 (59.4–80.7)
Limbic/Neocortical	97.8 (88.4–99.9)
Amygdala	14.3 (5.0–34.6)
Specificity	98.1 (90.1–99.9)
Positive predictive value	97.9 (89.1–99.9)
Negative predictive value	73.2 (62.0–82.2)
POSTMORTEM (n=56)
Variable	Value, % (95% CI)
Sensitivity	80.0 (62.7–90.5)
Limbic/Neocortical	90.0 (69.9–98.2)
Amygdala	60.0 (31.3–83.2)
Specificity	88.5 (71.0–96.0)
Positive predictive value	88.9 (71.9–96.2)
Negative predictive value	79.3 (61.6–90.2)