Table 2 –
Tidal volume and PEEP at 24 hours
| Characteristic Total n=86 | TV ≤ 8 mL/kg | p | PEEP appropriate for FIO2 | p |
|---|---|---|---|---|
|
| ||||
| Age group | ||||
| 1 month-<2 years | 23/39 (59%) | 0.04 | 17/39 (44%) | 0.15 |
| 2–5 years | 13/16 (81%) | 7/16 (44%) | ||
| 6–12 years | 7/19 (37%) | 14/19 (74%) | ||
| 13–<18 years | 5/12 (42%) | 7/12 (58%) | ||
|
| ||||
| Gender | ||||
| Female | 24/40 (60%) | 0.47 | 20/40 (50%) | 0.69 |
| Male | 24/46 (52%) | 25/46 (47%) | ||
|
| ||||
| Race | ||||
| White | 21/43 (49%) | 0.64 | 21/43 (49%) | 0.74 |
| Black or African American | 13/20 (65%) | 10/20 (50%) | ||
| Other/Mixed/Unspecified | 10/16 (63%) | 9/16 (56%) | ||
| Hispanic or Latino | 4/7 (57%) | 5/7 (71%) | ||
|
| ||||
| Weight category (≥2 years old, n=47) | ||||
| Normal/underweight | 16/22 (73%) | 0.046 | 13/22 (59%) | 0.76 |
| Overweight | 2/5 (40%) | 4/5 (80%) | ||
| Obese | 7/20 (35%) | 11/20 (55%) | ||
|
| ||||
| Tracheostomy tube present | ||||
| No | 40/75 (53%) | 0.33 | 40/75 (53%) | 0.75 |
| Yes | 8/11 (73%) | 5/11 (45%) | ||
|
| ||||
| pARDS cause | ||||
| Respiratory | 30/49 (61%) | 0.25 | 26/49 (53%) | 0.88 |
| Systemic | 18/37 (49%) | 19/37 (51%) | ||
|
| ||||
| pARDS severity | ||||
| Initial Mild | 19/36 (53%) | 0.55 | 25/43 (58%) | 0.49 |
| Moderate | 11/19 (58%) | 13/25 (52%) | ||
| Severe | 15/28 (54%) | 10/18 (56%) | ||
| N/A (non-invasive vent) | 3/3 (100%) | 3/3 (100%) | ||
| 24 hours Mild | 25/43 (58%) | 0.89 | 28/43 (65%) | 0.35 |
| Moderate | 13/25 (52%) | 11/25 (44%) | ||
| Severe | 10/18 (56%) | 6/18 (33%) | ||
|
| ||||
| Ventilator mode | ||||
| Pressure regulated volume control | 38/73 (52%) | 0.08 | 40/73 (55%) | 0.11 |
| Pressure control/pressure support | 9/11 (82%) | 3/11 (27%) | ||
| CPAP with pressure or volume support | 1 /2 (50%) | 2/2 (100%) | ||
|
| ||||
| pARDS in progress note at 24 hours | ||||
| No | 45/79 (57%) | 0.69 | 40/79 (51%) | 0.44 |
| Yes | 3/7 (43%) | 5/7 (71%) | ||
Notes: All were on conventional mechanical ventilation using Servo-i (Maquet corporation) in synchronized intermittent mechanical ventilation (SIMV) setting. Bold indicates p<0.05.