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. 2022 Sep 16;58:268–278. doi: 10.1016/j.jdsr.2022.09.001

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© 2022 Japanese Association for Dental Science

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 1 — Growth of the EMT-related literature. The first experimental analysis of epithelial–mesenchymal transition (EMT) in development was published in 1968. The relationship of EMT to growth factors was identified in 1989 and the transcriptional regulation of EMT was identified in 1994. More recent studies link EMT to metastasis, organ fibrosis and stem cells.

(retrieved from PubMed at https://pubmed.ncbi.nlm.nih.gov/ using the search terms: epithelial-mesenchymal transition, epithelial-mesenchymal transformation in April 2022)