Table 1.
Showing Baseline demographics, comorbidities, and descriptive complications among TAVR and SAVR with Heart Failure Octogenarian groups for both unmatched and propensity matched cohorts.
| Analyte |
Unmatched Cohort |
Propensity Matched Cohort |
||||
|---|---|---|---|---|---|---|
| TAVR-HF (n = 64,890) | SAVR-HF (n = 10,105) | p-value | TAVR-HF (n = 11,329) | SAVR-HF (n = 11,329) | p-value | |
| Age (median; IQRS) years | 86 (83–89) | 82 (81–84) | 86(23–89) | 82(81–84) | ||
| Year n (%) | ||||||
| 2015 | 3,480 (5.4) | 1,270 (12.6) | 0.000 | – | – | |
| 2016 | 17,230 (26.6) | 3,580 (35.4) | 0.000 | 0.000 | ||
| 2017 | 21,510 (33.1) | 2,825 (28) | 0.000 | 0.000 | ||
| 2018 | 22,675 (34.9) | 2,430 (24) | 0.000 | 0.000 | ||
| Sex n (%) | ||||||
| Male | 33,475 (51.6) | 6,455 (63.9) | 0.000 | 5,816 (51.3) | 5,816 (51.3) | 1.000 |
| Female | 31,415 (48.4) | 3,650 (36.1) | 0.000 | 5,513 (48.7) | 5,513 (48.7) | 1.000 |
| Race n (%) | ||||||
| White | 55,190 (90.5) | 8,160 (87.6) | 0.000 | 10,252 (90.5) | 10,272 (90.7) | 0.449 |
| Black | 2,175 (3.6) | 315 (3.4) | 0.000 | 402 (3.5) | 321.9 (2.8) | 0.449 |
| Hispanic | 2,700 (4.4) | 640 (6.9) | 0.000 | 502 (4.4) | 585.8 (5.2) | 0.449 |
| Asian/PI | 815 (1.3) | 185 (2) | 0.000 | 152 (1.3) | 143.8 (1.3) | 0.449 |
| Transfers (%) | ||||||
| Not Transferred | 59,770 (92.3) | 8,665 (86.1) | 0.000 | 10,476 (92.5) | 10,531 (93) | 0.391 |
| Transferred | 3,990 (6.2) | 1,235 (12.3) | 0.000 | 678 (6) | 567.9 (5) | 0.391 |
| Elective (%) | ||||||
| Non-elective | 13,110 (20.3) | 3,690 (36.6) | 0.000 | 2,273 (20.1) | 2,273 (20.1) | 1.000 |
| Elective | 51,380 (79.7) | 6,385 (63.4) | 0.000 | 9,056 (79.9) | 9,056 (79.9) | 1.000 |
| Hospital Bed Size n (%) [Values vary by Region & Control] | ||||||
| Small | 4,275 (7) | 850 (9.6) | 0.003 | 771 (6.8) | 788 (7) | 0.973 |
| Medium | 12,525 (20.4) | 1,940 (22) | 0.003 | 2,303 (20.3) | 2,269 (20) | 0.973 |
| Large | 61,415 (72.6) | 8,835 (68.4) | 0.003 | 8,255 (72.9) | 8,272 (73) | 0.973 |
| Hospital Location & Teaching Status n (%) | ||||||
| Rural | 645 (1.1) | 175 (2) | 0.000 | 115 (1) | 100.8 (0.9) | 0.861 |
| Urban Non-Teaching | 6,915 (10.1) | 1,320 (14.9) | 0.000 | 1,071 (9.5) | 1,099.4 (9.7) | 0.861 |
| Urban Teaching | 54,575 (88.9) | 7,340 (83.1) | 0.000 | 10,143 (89.5) | 10,128.8 (89.4) | 0.861 |
| Hospital Region n (%) | ||||||
| Northeast | 14,875 (24.2) | 2,130 (24.1) | 0.266 | 2,773 (24.5) | 2,797.3 (24.7) | 0.003 |
| Midwest | 14,255 (23.2) | 2,135 (24.2) | 0.266 | 2,549 (22.5) | 2,916.9 (25.7) | 0.003 |
| South | 19,825 (32.3) | 2,600 (29.4) | 0.266 | 3,748 (33.1) | 2,939.2 (25.9) | 0.003 |
| West | 12,460 (20.3) | 1,970 (22.3) | 0.266 | 2,259 (19.9) | 2,675 (23.6) | 0.003 |
| Weekend Admission n (%) | ||||||
| Monday-Friday | 62,365 (96.1) | 9,320 (92.2) | 0.000 | 10,908 (96.3) | 10,908 (96.3) | 1.000 |
| Saturday-Sunday | 2,530 (3.9) | 785 (7.8) | 0.000 | 421(3.7) | 421(3.7) | 1.000 |
| Comorbidities | ||||||
| Pulmonary Circulation Disorders | 13,000 (20) | 2190 (21.7) | 0.117 | 2234 (19.7) | 2234 (19.7) | 1.000 |
| Chronic Pulmonary Disease | 16,825 (25.9) | 2,200 (21.8) | 0.000 | 2932 (25.9) | 2932 (25.9) | 1.000 |
| Diabetes Uncomplicated | 9,325 (14.4) | 1,215 (12) | 0.006 | 1573 (13.9) | 1573 (13.9) | 1.000 |
| Diabetes Complicated | 11,190 (17.2) | 1,665 (16.5) | 0.423 | 2001 (17.7) | 2001(17.7) | 1.000 |
| Hypothyroidism | 14,670 (22.6) | 1,665 (16.5) | 0.000 | 2590 (22.9) | 2590 (22.9) | 1.000 |
| Renal Failure | 26,125 (40.3) | 3,190 (31.6) | 0.000 | 4513 (39.8) | 4513 (39.8) | 1.000 |
| Peptic Ulcer Disease (excluding bleeding) | 410 (0.6) | 100 (1) | 0.066 | 71 (0.6) | 71 (0.6) | 1.000 |
| Lymphoma | 475 (0.7) | 50 (0.5) | 0.233 | 89 (0.8) | 89 (0.8) | 1.000 |
| Metastatic Cancer | 325 (0.5) | 20 (0.2) | 0.058 | 52 (0.5) | 52 (0.5) | 1.000 |
| Solid Tumor Without Metastasis | 1,475 (2.3) | 180 (1.8) | 0.190 | 251 (2.2) | 251 (2.2) | 1.000 |
| Rheumatoid Arthritis/Collagen Vascular | 2,910 (4.5) | 305 (3) | 0.003 | 513 (4.5) | 513 (4.5) | 1.000 |
| Coagulopathy | 8,420 (13) | 4,455 (44.1) | 0.000 | 1421 (12.5) | 1421 (12.5) | 1.000 |
| Obesity | 7,605 (11.7) | 1,360 (13.5) | 0.028 | 1345 (11.9) | 1345 (11.9) | 1.000 |
| Weight Loss | 2,495 (3.8) | 965 (9.5) | 0.000 | 442 (3.9) | 442 (3.9) | 1.000 |
| Fluid and Electrolyte Disorders | 10,170 (15.7) | 4,500 (44.5) | 0.000 | 1758 (15.5) | 1758 (15.5) | 1.000 |
| Blood Loss Anemia | 805 (1.2) | 120 (1.2) | 0.843 | 137 (1.2) | 137 (1.2) | 1.000 |
| Deficiency Anemia | 2,765 (4.3) | 390 (3.9) | 0.416 | 479 (4.2) | 479 (4.2) | 1.000 |
| Alcohol Abuse | 395 (0.6) | 135 (1.3) | 0.000 | 69 (0.6) | 69 (0.6) | 1.000 |
| Drug Abuse | 75 (0.1) | 15 (0.1) | 0.691 | 15 (0.1) | 15 (0.1) | 1.000 |
| HD | 545 (0.8) | 135 (1.3) | 0.024 | 105 (0.9) | 105 (0.9) | 1.000 |
| HTN | 10,990 (16.9) | 2,670 (26.4) | 0.000 | 1,694 (15) | 1,694 (15) | 1.000 |
| PAD | 7,990 (12.3) | 860 (8.5) | 0.000 | 1,384 (12.2) | 1,384 (12.2) | 1.000 |
| Family History of CAD | 4,605 (7.1) | 730 (7.2) | 0.834 | 790 (7) | 790 (7) | 1.000 |
| OSA | 6005 | 965 | 0.600 | 1,032 (9.1) | 1,032 (9.1) | 1.000 |
| Liver Disease | 795 (1.2) | 155 (1.5) | 0.279 | 139 (1.2) | 139 (1.2) | 1.000 |
| Alcohol | 355 (0.5) | 135 (1.3) | 0.000 | 62 (0.5) | 62 (0.5) | 1.000 |
| Smoking | 23,215 (35.8) | 3,485 (34.5) | 0.268 | 4,103 (36.2) | 4,103 (36.2) | 1.000 |
| Pneumonia | 995 (1.5) | 575 (5.7) | 0.000 | 169 (1.5) | 169 (1.5) | 1.000 |
| Hx of PCI | 1,790 (2.8) | 135 (1.3) | 0.000 | 302 (2.7) | 302 (2.7) | 1.000 |
| Hx of CABG | 10,665 (16.4) | 465 (4.6) | 0.000 | 1,837 (16.2) | 1,837 (16.2) | 1.000 |
| Previous MI | 8,700 (13.4) | 760 (7.5) | 0.000 | 1,530 (13.5) | 1,530 (13.5) | 1.000 |
| CAD | 46,430 (71.5) | 7,105 (70.3) | 0.279 | 8,106 (71.6) | 8,106 (71.6) | 1.000 |
| Syncope | 715 (1.1) | 115 (1.1) | 0.889 | 126 (1.1) | 126 (1.1) | 1.000 |
| Endocarditis | 215 (0.3) | 290 (2.9) | 0.000 | 42 (0.4) | 42 (0.4) | 1.000 |
*Abbreviations: PCI: Percutaneous Coronary Intervention; CABG: Coronary Artery Bypass Graft; CAD: Coronary Artery Disease; MI: Myocardial infarction; AIDS: Acquired Immunodeficiency Syndrome; HIV: Human Immunodeficiency Virus; Peripheral Artery Disease (PAD); Hypertension (HTN); Hemodialysis (HD); CVA (cerebral vascular accident); SCA (sudden cardiac arrest); MCS (mechanical circulatory support); AKI (acute kidney injury); OSA (obstructive sleep apnea).