Table 2.
Unmatched Cohort and Propensity Matched Outcomes of SAVR vs TAVR Among Heart Failure, Heart Failure with reduced and preserved ejection fraction in Octogenarian Population.
| Outcomes |
Unmatched Cohort |
Propensity Matched Cohort |
||||
|---|---|---|---|---|---|---|
| TAVR-HF n (%) | SAVR-HF n (%) | p-value | TAVR-HF n (%) | SAVR-HF n (%) | p-value | |
| In-Hospital Mortality | 1145 (1.8) | 695 (6.9) | 0.000 | 206 (1.8) | 926.6 (8.2) | 0.000 |
| HFrEF | 185 (1.9) | 195 (7.7) | 0.000 | 33 (2) | 146 (8.7) | 0.001 |
| HFpEF | 580 (1.5) | 210 (5.2) | 0.000 | 107 (1.6) | 325.9 (4.8) | 0.006 |
| Post-procedural stroke | 605 (0.9) | 100 (1) | 0.080 | 104 (0.9) | 54.6 (0.5) | 0.251 |
| SCA | 6450 (9.9) | 2045 (20.2) | 0.000 | 1087 (9.6) | 1495.5 (13.2) | 0.018 |
| HFrEF | 990 (10) | 490 (19.4) | 0.000 | 161 (9.5) | 238.2 (14.1) | 0.362 |
| HFpEF | 3795 (9.8) | 800 (19.8) | 0.000 | 651 (9.5) | 798.6 (11.7) | 0.346 |
| AKI | 11,265 (17.4) | 4125 (40.8) | 0.000 | 1951 (17.2) | 3099.2 (27.4) | 0.000 |
| HFrEF | 2080 (21) | 1140 (45.1) | 0.000 | 357 (21.2) | 681.7 (40.4) | 0.002 |
| HFpEF | 6040 (15.7) | 1495 (37) | 0.000 | 1053 (15.4) | 2134.8 (31.3) | 0.000 |
| Major Bleeding | 1185 (1.8) | 180 (1.8) | 0.891 | 195 (1.7) | 111.7 (1) | 0.104 |
| HFrEF | 220 (2.2) | 60 (2.4) | 0.831 | 34 (2) | 17.1 (1) | 0.418 |
| HFpEF | 675 (1.7) | 65 (1.6) | 0.781 | 111 (1.6) | 60.3 (0.9) | 0.379 |
| Transfusion | 17,110 (26.4) | 6805 (67.3) | 0.000 | 2931 (25.9) | 3559.6 (31.4) | 0.026 |
| HFrEF | 2995 (30.2) | 1810 (71.7) | 0.000 | 513 (30.4) | 561 (33.3) | 0.651 |
| HFpEF | 9430 (24.4) | 2570 (63.5) | 0.000 | 1632 (23.9) | 1943.2 (28.5) | 0.232 |
| Cardiogenic Shock | 1180 (1.8) | 995 (9.8) | 0.000 | 202 (1.8) | 391.4 (3.5) | 0.000 |
| HFrEF | 310 (3.1) | 375 (14.9) | 0.000 | 53 (3.1) | 105.9 (6.3) | 0.078 |
| HFpEF | 410 (1.1) | 270 (6.7) | 0.000 | 75 (1.1) | 224.8 (3.3) | 0.001 |
| Mechanical Circulatory Support (LVAD or pVAD or ECMO) | 535 (0.8) | 735 (7.3) | 0.000 | 90 (0.8) | 495.5 (4.4) | 0.000 |
| HFrEF | 165 (1.7) | 315 (12.5) | 0.000 | 28 (1.7) | 201.4 (11.9) | 0.000 |
| HFpEF | 175 (0.5) | 130 (3.2) | 0.000 | 29 (0.4) | 209.4 (3.1) | 0.000 |
Abbreviations: CVA: Cerebral Vascular Accident; TAVR: Transaortic Valve Replacement; SAVR: Surgical Aortic Valve Replacement; SCA: Sudden Cardiac Arrest; AKI: Acute Kidney Injury; LVAD: Left Ventricular Assist Device; pVAD: Percutaneous Ventricular Assist Device; ECMO: Extracorporeal Membrane Oxygenation; HF: Heart Failure; HFrEF: Heart Failure with reduced ejection fraction; HFpEF: Heart Failure with preserved ejection fraction.