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. 2022 Sep 13;12(6):782–797. doi: 10.1016/j.jobcr.2022.09.001

Table 1.

Bioceramics for alveolar bone and cementum regeneration.

Bioceramics Target tissue Features Ref
Hydroxyapatite (HA) Cementum, Alveolar bone Similar composition to the inorganic phase of bone
Osteoconductive
Slow degradation
29,31
tricalcium phosphates (TCP) Alveolar bone, cementum Similar composition to the inorganic phase of bone
Higher stability
Osteoconductive
Bioabsorbable
Β-TCP: Similar degradation kinetic to the autologous grafts
32, 33, 34
Bioactive glass Alveolar bone, cementum Osteoconductive and osteoblast cell differentiation
Similar composition to the inorganic phase of bone
Biocompatible with the different degradation rate
Degradation products improve the osteogenesis, angiogenesis, and antibacterial activities
28,35,36
Nagelschmidtite (Ca7Si2P2O16) Alveolar bone, cementum Suitable mechanical properties and degradation rate for spongy bone regeneration
Favorable apatite formation and angiogenesis
Improved osteogenesis and cementogenesis compared to HA and TCP
37
Silicocarnotite (Ca2SiO4.Ca(PO4)2) Alveolar bone, cementum Better mechanical properties and manufacturability compared to Nagelschmidtite
Better bone formation, osteogenesis, and cementogenesis compared to the HA
37
Nurse's Ass-phase (2Ca2SiO4.Ca3(PO4)2) Alveolar bone, cementum Favorable bone formation and degradation rate
Lower bone formation compares to other Silicate based bioceramics
37
Other silicate-based bioceramics: Alveolar bone, cementum Great cellular properties
Excellent ability in improving cell proliferation and differentiation to osteogenic of PDLCs
Great cementum formation compares to other bioceramics
Increasing expression of osteocalcin and bone sialoprotein
30
Akermanite (Ca2MgSi2O7)
Bredigite (Ca7MgSi4O16)
Baghdadite (Ca3ZrSi2O9)
Diopside (CaMgSi2O6)