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. 2022 Sep 20;12:15693. doi: 10.1038/s41598-022-20007-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Prognostic value of IRGPI in immunotherapy. (A) The proportions of immune cells in different IRGPI groups. (B) Comparison of TMB and PD-L1 expression in different IRGPI groups. (C) TIDE, MSI, and T cell exclusion and dysfunction score in different IRGPI groups. (D) Kaplan–Meier survival analysis of the IRGPI groups in the IMvigor210 cohort. (E) IMvigor210 cohort of CR/PR and SD/PD in different IRGPI groups. (F) PRJEB25780 cohort of CR/PR and SD/PD in different IRGPI groups. (G) ROC analysis of IRGPI, TIS, and TIDE on overall survival at 1-, 3-, and 5-years OS in TCGA-STAD cohort. [Figures created by R, version 4.0.4.].