Table 1.
Demographic characteristics and flow cytometry results in the control group and in the TB group.
| CAP group (n = 48) | TB group (n = 48) | p-value | |
|---|---|---|---|
| Age, mean ± SD | 42.06 ± 19.11 | 42.06 ± 19.11 | 1.0 |
| Sex | |||
| Male, c (%) | 35 (73%) | 35 (73%) | χ 1.0 |
| Female, c (%) | 13 (27%) | 13 (27%) | |
| Geographical origin | |||
| White–Italia | 41 (85%) | 21 (44%) | χ <0.0001* |
| White-Southeast Europea | 0 (0%) | 8 (17%) | χ 0.006* |
| Black–West Africab | 6 (13%) | 15 (31%) | χ 0.046* |
| Black – Central Africac | 1 (2%) | 4 (8%) | χ 0.4 |
| Flow cytometry, median (Q1; Q3) | |||
| TL, c (cells/μL) | 1413.1 (1262.0; 1881.8) | 961.7 (676.8; 1371.3) | <0.0001* |
| CD4+, c (cells/μL) | 913.3 (752.2, 1162.4) | 490.0 (417.3, 795.1) | <0.0001* |
| CD4+, % | 46.26 (39.35; 52.98) | 42.28 (37.52; 46.98) | 0.03* |
| CD8+, c (cells/μL) | 463.4 (349.9; 645.9) | 354.9 (219.3; 533.4) | 0.02* |
| CD8+, % | 21.80 (16.83; 28.78) | 27.30 (20.88; 32.25) | 0.02* |
| BL, c (cells/μL) | 165.2 (108.5; 257.6) | 113.7 (59.4; 206.1) | 0.001* |
| BL, % | 7.9 (5.6; 11.7) | 8.6 (6.0; 12.2) | 0.62 |
| NKL, c (cells/μL) | 303.1 (193.1; 523.0) | 187.4 (92.66; 300.9) | 0.0009* |
| NKL, % | 15.1 (10.4; 23.6) | 13.7 (8.1; 19.7) | 0.38 |
| CD4+/CD8+ | 1.98 (1.59; 3.05) | 1.56 (1.23; 2.05) | 0.0096* |
CAP, community-acquired pneumonia; TB, tuberculosis; TL, total lymphocytes; BL, B-lymphocytes, NKL, natural killer lymphocytes; SD, standard deviation; Q1, first quartile; Q3 third quartile. aSoutheast Europe: patients coming from Bulgaria, Romania, and Serbia; bWest Africa: patients coming from The Gambia, Ghana, Nigeria, Senegal, Sierra Leone, and Togo; cCentral Africa: patients coming from Cameroon, the Democratic Republic of the Congo, Gabon. (χ) Assessed with chi-square test. p < 0.05 is denoted by *.