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. 2022 Sep 7;13:970553. doi: 10.3389/fphar.2022.970553

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Copyright © 2022 Wei, Xiang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Interaction of NAMPT with inhibitory compounds: (A). Interaction of NAMPT with the specific inhibitor FK866. (B). Interaction of NAMPT with specific inhibitor GEN617. (C). Interaction of NAMPT with specific inhibitor CHS828. (D). Interaction of NAMPT with A1293201. (E). X-ray crystal image of NAMPT, the enzyme has two symmetrical binding sites.