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. 2022 Sep 7;9:999836. doi: 10.3389/fnut.2022.999836

TABLE 6.

Association between blood selenium concentration (μmol/L) and CAL (mm), and stratified by sex, race/ethnicity, age, and diabetes history.

Model 1 β (95% CI) Model 2 β (95% CI) Model 3 β (95% CI)
Blood selenium −0.1714 (−0.2420, −0.1008)*** −0.1948 (−0.2607, −0.1290)*** −0.1056 (−0.1647, −0.0465)***
Lowest quartiles Reference Reference Reference
2nd −0.1900 (−0.2700, −0.1100)*** −0.1921 (−0.2665, −0.1177)*** −0.1057 (−0.1720, −0.0395)**
3rd −0.1870 (−0.2653, −0.1086)*** −0.2014 (−0.2744, −0.1284)*** −0.0869 (−0.1524, −0.0215)**
4th −0.2319 (−0.3113, −0.1525)*** −0.2597 (−0.3339, −0.1856)*** −0.1454 (−0.2118, −0.0789)***
P for trend <0.001 <0.001 <0.001
Stratified by sex
Male −0.3919 (−0.5153, −0.2686)*** −0.3659 (−0.4825, −0.2493)*** −0.1974 (−0.3007, −0.0942)***
Female −0.0787 (−0.1534, −0.0040)* −0.0686 (−0.1392, 0.0020) −0.0346 (−0.0995, 0.0303)
Stratified by race/ethnicity
Non−Hispanic White −0.1427 (−0.2386, −0.0468)** −0.1794 (−0.2705, −0.0882)*** −0.1195 (−0.1985, −0.0405)**
Non-Hispanic Black −0.1638 (−0.4045, 0.0769) −0.2661 (−0.4877, −0.0446)* −0.0858 (−0.2944, 0.1227)
Mexican American 0.0040 (−0.3188, 0.3268) −0.1024 (−0.3991, 0.1943) 0.1235 (−0.1672, 0.4143)
Other −0.1990 (−0.3484, −0.0496)** −0.2783 (−0.4173, −0.1393)*** −0.1629 (−0.2941, −0.0317)*
Stratified by age
30–44 years −0.1716 (−0.2747, −0.0684)** −0.2035 (−0.3034, −0.1037)*** −0.1581 (−0.2516, −0.0646)***
45–59 years −0.3407 (−0.4976, −0.1838)*** −0.3245 (−0.4743, −0.1746)*** −0.1233 (−0.2525, 0.0060)
60–74 years −0.0989 (−0.2097, 0.0119) −0.1050 (−0.2105, 0.0004) −0.0662 (−0.1582, 0.0259)
≥75 years −0.1482 (−0.4747, 0.1783) −0.1818 (−0.4893, 0.1257) −0.1573 (−0.4602, 0.1456)
Stratified by diabetes history
Diabetic −0.3435 (−0.5703, −0.1166)** −0.3064 (−0.5248, −0.0881)** −0.0854 (−0.2871, 0.1164)
Non-diabetic −0.1557 (−0.2278, −0.0835)*** −0.1828 (−0.2504, −0.1153)*** −0.1130 (−0.1733, −0.0527)***

Model 1, unadjusted.

Model 2, age, sex, race/ethnicity were adjusted.

Model 3, age, sex, race/ethnicity, BMI, income-poverty ratio, education, vitamin D, smoking status, diabetes, frequency per week using floss and mouthwash, periodontal treatment, hypertension, hyperlipidemia, BMD, congestive heart failure, coronary heart disease, angina pectoris, heart attack, stroke, physical activity, and calcium intake were adjusted. In the subgroup analysis stratified, the model is not adjusted for the stratification variable itself. *P < 0.05; **P < 0.01; ***P < 0.001.