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Schematic overview of the different strategies to improve cells pretransplantation. Olfactory ensheathing cells are isolated and purified from biopsies of olfactory mucosa or olfactory bulb tissue. The cells can be modulated by exposure to low oxygen, stimulated to improve migratory and phagocytic properties, and cultured in three-dimensional constructs prior to transplantation at the site of spinal cord injury.
