Factors and levels of Box–Behnken design.
| Factors | Experimental level | ||
|---|---|---|---|
| Low (−1) | Medium (0) | High (+1) | |
| X 1: molar ratio | 1 | 2 | 3 |
| X 2: water content, % | 20 | 30 | 40 |
| X 3: extraction time, min | 10 | 30 | 50 |
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