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. Author manuscript; available in PMC: 2022 Sep 21.
Published in final edited form as: Cell Rep. 2022 Aug 16;40(7):111187. doi: 10.1016/j.celrep.2022.111187

Figure 3. Effects of dietary protein titration on hepatic transcriptome.

Figure 3.

Adult male B6D2F1 mice (4/group) were fed ad libitum for 1 week on an isocaloric semi-purified diet of the indicated protein calorie percentage, and liver transcriptomes were analyzed.

(A) Multidimensional scaling distances.

(B) Venn diagram of significantly differentially expressed genes in 0%, 2%, and 6% protein groups versus 18% control.

(C) Clustering analysis separated into four major cluster patterns.

(D–G) Pathway enrichment in the 4 major clusters identified in (C).

See also Figure S3.