FIGURE 1.

X‐ray structure of EhLOx wild‐type and comparison with AvLOx structure. (a) Overall structure of EhLOx wild‐type. (b) Active site of the EhLOx structure bound with d‐lactate form ligand. Met207 showed alternative conformation, A and B, indicating its flexibility. Each monomer was shown in green, orange, magenta, and blue. The flexible loop regions (187–218) are colored in red and all β‐strands are colored in yellow. (c) Active site of the AvLOx structure bound with pyruvate from PDB ID 2E77 chain D