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. 2022 Jun 14;87(13):8819–8823. doi: 10.1021/acs.joc.2c00862

Scheme 5. Scope of Kinetic Resolution.

Scheme 5

Using 1.0 equiv of n-BuLi, 1.1 equiv of (+)-sparteine (and 2 h for 3e and 3h).

Using (−)-sparteine.