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. 2022 Sep 20;17(1):1495–1506. doi: 10.1515/med-2022-0551

Table 1.

Gene sets enriched in NK cells from AML patients

Gene sets Size ES NES Nom p-val FDR q-val FWER p-val Rank at max
GOBP_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION 71 0.35 2.13 0.006 1 0.229 4,265
GOCC_RESPIRATORY_CHAIN_COMPLEX 75 0.45 2.07 0 1 0.254 2,812
GOCC_PROTEASOME_CORE_COMPLEX 18 0.78 2.01 0 1 0.281 2,147
GOBP_PROTEASOMAL_UBIQUITIN_INDEPENDENT_PROTEIN_CATABOLIC_PROCESS 20 0.69 2.01 0 1 0.281 2,948
GOBP_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER 67 0.38 2 0 1 0.281 2,402
GOBP_ATP_SYNTHESIS_COUPLED_ELECTRON_TRANSPORT 89 0.43 2 0 1 0.281 2,812
GOCC_NADH_DEHYDROGENASE_COMPLEX 48 0.52 1.97 0 1 0.308 2,811
GOCC_RESPIRASOME 88 0.4 1.94 0 1 0.323 3,222
GOBP_ANAPHASE_PROMOTING_COMPLEX_DEPENDENT_CATABOLIC_PROCESS 71 0.35 1.94 0.02 1 0.323 2,290
GOBP_NEGATIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CY 23 0.35 1.92 0.033 1 0.359 4,265
GOBP_MITOCHONDRIAL_ELECTRON_TRANSPORT_NADH_TO_UBIQUINONE 52 0.49 1.89 0 1 0.418 2,811
GOBP_OXIDATIVE_PHOSPHORYLATION 122 0.36 1.87 0 1 0.435 2,812
GOBP_REGULATION_OF_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION 61 0.37 1.86 0 1 0.448 4,010
GOBP_REGULATION_OF_CELLULAR_AMINO_ACID_METABOLIC_PROCESS 51 0.4 1.85 0.022 1 0.448 2,290
GOBP_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS 58 0.36 1.85 0.026 1 0.448 2,290
GOMF_SCAFFOLD_PROTEIN_BINDING 29 0.36 1.85 0 1 0.448 5,778
GOCC_CYCLIN_DEPENDENT_PROTEIN_KINASE_HOLOENZYME_COMPLEX 27 0.39 1.85 0.018 1 0.451 3,005
GOBP_POSITIVE_REGULATION_OF_B_CELL_PROLIFERATION 24 0.47 1.84 0 1 0.451 4,122
GOCC_ENDOPEPTIDASE_COMPLEX 64 0.35 1.84 0 1 0.457 2,363
HP_LIMB_GIRDLE_MUSCLE_ATROPHY 18 0.46 1.83 0.01 1 0.49 2,462