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. 2022 Sep 21;20:308. doi: 10.1186/s12916-022-02510-1

Table 1.

Baseline characteristics of participants with OA according to serum 25(OH)D concentrations

Serum 25(OH)D concentrations (nmol/L) P-value
Total < 25.00 25.00–49.99 50.00–74.99 ≥ 75.00
N(%) 2556 (100.00) 100 (3.91) 589 (23.04) 955 (37.36) 912 (35.68)
Age (years) 63.01 ± 13.79 60.12 ± 14.26 61.84 ± 14.06 62.59 ± 13.91 64.52 ± 13.30 <0.01
Gender <0.01
 Male (%) 917 (35.88) 25 (25.00) 207 (35.14) 394 (41.26) 291 (31.91)
 Female (%) 1639 (64.12) 75 (75.00) 382 (64.86) 561 (58.74) 621 (68.09)
Race/ethnicity <0.01
 Mexican American (%) 238 (9.31) 17 (17.00) 85 (14.43) 88 (9.21) 48 (5.26)
 Other Hispanic (%) 157 (6.14) 5 (5.00) 44 (7.47) 70 (7.33) 38 (4.17)
 Non-Hispanic White (%) 1667 (65.22) 29 (29.00) 285 (48.39) 631 (66.07) 722 (79.17)
 Non-Hispanic Black (%) 376 (14.71) 44 (44.00) 143 (24.28) 116 (12.15) 73 (8.00)
 Other race—including multi-racial (%) 118 (4.62) 5 (5.00) 32 (5.43) 50 (5.24) 31 (3.40)
Education (%) <0.01
 Less than high school 613 (23.99) 35 (35.00) 180 (30.56) 219 (22.93) 179 (19.63)
 High school or equivalent 620 (24.27) 24 (24.00) 131 (22.24) 226 (23.66) 239 (26.21)
 College or above 1322 (51.74) 41 (41.00) 278 (47.20) 510 (53.40) 493 (54.06)
 Not recorded 1 (0.04) 0 (0.00) 0 (0.00) 0 (0.00) 1 (0.11)
Smoking status (%) <0.01
 Every day 375 (14.67) 23 (23.00) 110 (18.68) 133 (13.93) 109 (11.95)
 Some day 53 (2.07) 3 (3.00) 16 (2.72) 18 (1.88) 16 (1.75)
 Not at all 903 (35.33) 26 (26.00) 187 (31.75) 358 (37.49) 332 (36.40)
 Not recorded 1225 (47.93) 48 (48.00) 276 (46.86) 446 (46.70) 455 (49.89)
Alcoholic ≥ 4 drinks/day (%) 0.03
 Yes 303 (11.85) 13 (13.00) 75 (12.73) 131 (13.72) 84 (9.21)
 No 1488 (58.22) 52 (52.00) 327 (55.52) 547 (57.28) 562 (61.62)
 Not recorded 765 (29.93) 35 (35.00) 187 (31.75) 277 (29.01) 266 (29.17)
Family poverty income ratio 2.71 ± 1.62 2.29 ± 1.53 2.39 ± 1.56 2.77 ± 1.62 2.89 ± 1.63 <0.01
Weight (kg) 83.90 ± 22.82 97.08 ± 31.80 88.04 ± 24.17 84.76 ± 22.53 78.98 ± 19.74 <0.01
BMI (kg/m2) 30.74 ± 7.60 36.55 ± 10.99 32.49 ± 7.97 30.62 ± 7.18 29.13 ± 6.78 <0.01
Waist circumference (cm) 103.57 ± 15.97 113.69 ± 20.71 107.40 ± 15.77 103.54 ± 15.56 100.24 ± 15.05 <0.01
Duration of OA (%) 0.20
 Less than 5 years 745 (29.15) 26 (26.00) 163 (27.67) 300 (31.41) 256 (28.07)
 5–10 years 486 (19.01) 22 (22.00) 107 (18.17) 192 (20.10) 165 (18.09)
 10-20 years 712 (27.86) 22 (22.00) 162 (27.50) 266 (27.85) 262 (28.73)
 More than 20 years 597 (23.36) 29 (29.00) 151 (25.64) 193 (20.21) 224 (24.56)
 No Recorded 16 (0.63) 1 (1.00) 6 (1.02) 4 (0.42) 5 (0.55)
Hypertension (%) 1462 (57.20) 67 (67.00) 346 (58.74) 518 (54.24) 531 (58.22) <0.01
Diabetes (%) 455 (17.80) 30 (30.00) 144 (24.45) 162 (16.96) 119 (13.05) <0.01

Data are presented as mean ± SD or n (%)