Table 1.
Antimicrobial peptides effective against viral infections.
| AMP | Target | Source | References |
|---|---|---|---|
| Gloverin | Autographa californica M nucleopolyhedrovirus (AcMNPV) | Trichoplusia ni larvae | Moreno-Habel et al. (2012) |
| α-defensin-5 (HD-5) | Human Immunodeficiency Virus-1 (HIV-1), Human papillomavirus 16 (HPV) | Humans | Furci et al. (2012); Wiens and Smith (2017) |
| Lactoferrin | Influenza virus, Hepatitis C virus (HCV), Dengue Virus (DENV) | Humans | Ammendolia et al. (2012);El-Fakharany et al. (2013);Chen et al. (2017) |
| Elafin and Trappin-2 | HIV-1 | Humans | Drannik et al. (2013) |
| Griffithsin (GRFT) | Hepatitis C Virus (HCV), Japanese encephalitis virus (JEV), Middle East respiratory syndrome coronavirus (MERS-CoV) | Griffithsia sp (red alga) | Takebe et al. (2013);Ishag et al. (2016);Millet et al. (2016);Derby et al. (2018) |
| Cycloviolacin Y5 and Cycloviolacin VY1 | Influenza A virus (IAV) | Viola yedoensis plant | Liu et al. (2014) |
| Hepcidin | IAV, HIV-1, HCV, and Hepatitis B Virus (HBV) | Humans | Armitage et al. (2014);Rodriguez et al. (2014) |
| Cathelicidin (LL-37) | IAV, HCV, Respiratory syncytial virus (RSV), DENV type 2, Venezuelan equine encephalitis virus (VEEV) | Humans | Tripathi et al. (2014);Harcourt et al. (2016);Matsumura et al. (2016);Alagarasu et al. (2017);Ahmed et al. (2019); |
| Lectin (NICTABA) | IAV, IBV, DENV type 2, Herpes Simplex Virus (HSV) types 1 and 2, HIV-1/2 | Nicotiana tabacum plant | Gordts et al. (2015) |
| Alstotides | Infectious bronchitis virus (IBV), DENV | Alstonia scholaris plant | Nguyen et al. (2015) |
| A. elatior lectin (AEL) | Vesicular Stomatitis Virus (VSV), Coxsackie Virus B4, and RSV | Aspidistra elatior plant | Xu et al. (2015) |
| Cathelicidins (Protegrin-1, and SMAP-29) | Human rhinoviruses (HRVs) | Humans | Sousa et al. (2017) |
| Cathelicidins (GF-17 and BMAP-18) | Zika virus (ZIKV) | Humans | He et al. (2018) |
| C-lysozyme | Nucleopolyhedrovirus (NPV) | Bombyx mori | Chen et al. (2018) |
| Lectin (TCLL) | Chikungunya virus (CHIKV) and Sindbis virus (SINV) | Tamarindus indica plant | Kaur et al. (2019) |
| Dermaseptins | HSV-1, HSV-2, HIV-1, and rabies virus | Agalychnis and Phyllomedusa family | Bartels et al. (2019) |
| Brevinin (1BYa and 1BYc) | Ebola virus, HIV-1 and HSV-1 | Rana boylii | Zohrab et al. (2019) |
| Temporin-SHa (SHa) and its synthetic analog [K3]SHa. | HSV-1 | North African ranid frog Pelophylax saharicus | Roy et al. (2019) |
| Brevinin-2GHk, | ZIKV | Fejervarya limnocharis | Xiong et al. (2021) |
| Fejerlectin | HIV-1 | Fejervarya limnocharis | Xiong et al. (2021) |
| AR-23 | HSV-1, Measles morbillivirus (MeV), Human parainfluenza virus (HPIV-2), HCoV-229E, and severe acute respiratory syndrome coronavirus (SARS-CoV-2) | Rana tagoi | Chianese et al. (2022) |