Table 1.
Baseline characteristics of the study population
| Characteristic | Overall (n=100) | Group C (n=25) | Group T (n=25) | Group V (n=25) | Group T + V (n=25) | P |
|---|---|---|---|---|---|---|
| Age (year) | ||||||
| Mean±s.d. | 64.1±6.2 | 67.2±5.1 | 63.6±4.5 | 61.9±6.6 | 63.7±7.4 | 0.019 |
| Median (range) | 64 (49–76) | 65 (60–76) | 63 (54–70) | 63 (49–74) | 63 (50–75) | |
| BMI (kg m−2) | ||||||
| Mean±s.d. | 23.8±2.5 | 23.5±2.5 | 24.8±2.5 | 23.1±1.8 | 23.8±2.9 | 0.102 |
| Median (range) | 23.7 (16.1–30.8) | 23.5 (18.3–30.1) | 24.8 (19.9–30.8) | 22.8 (19.7–27.7) | 23.7 (16.1–30.5) | |
| PSA (ng ml−1) | ||||||
| Mean±s.d. | 10.1±5.1 | 12.1±7.0 | 9.4±4.5 | 10.2±4.0 | 8.8±3.7 | 0.135 |
| Median (range) | 9.0 (3.3–29.9) | 10.1 (3.3–29.9) | 8.3 (5.0–29.4) | 9.5 (5.0–19.5) | 8.0 (4.4–16.6) | |
| Stage, n (%) | ||||||
| T2a | 59 (59.0) | 15 (60.0) | 13 (52.0) | 16 (64.0) | 15 (60.0) | 0.853 |
| T2b | 22 (22.0) | 5 (20.0) | 8 (32.0) | 5 (20.0) | 4 (16.0) | 0.552 |
| T2c | 19 (19.0) | 5 (20.0) | 4 (16.0) | 4 (16.0) | 6 (24.0) | 0.870 |
| Gleason score, n (%) | ||||||
| 6 | 29 (29.0) | 9 (36.0) | 5 (20.0) | 7 (28.0) | 8 (32.0) | 0.637 |
| 7 | 71 (71.0) | 16 (64.0) | 20 (80.0) | 18 (72.0) | 17 (68.0) | 0.637 |
| Type of surgery, n (%) | ||||||
| LRP | 72 (72.0) | 17 (68.0) | 18 (72.0) | 20 (80.0) | 17 (68.0) | 0.755 |
| RARP | 28 (28.0) | 8 (32.0) | 7 (28.0) | 5 (20.0) | 8 (32.0) | 0.755 |
| Baseline IIEF-5 score | ||||||
| Mean±s.d. | 21.6±2.0 | 20.7±1.8 | 21.8±2.0 | 23.5±1.7 | 23.0±2.2 | 0.147 |
| Median (range) | 20 (17–25) | 21 (18–25) | 21 (20–25) | 22 (20–25) | 21 (20–25) | |
| PLNES | ||||||
| Mean±s.d. | 7.7±1.5 | 7.6±1.7 | 8.1±1.1 | 7.5±1.6 | 7.4±1.7 | 0.442 |
| Median (range) | 7.6 (4.5–11.5) | 7.5 (4.6–11.5) | 8.2 (6.2–10.5) | 7.6 (4.5–10.5) | 7.5 (4.8–10.6) |
Group C: control group; Group T: tadalafil 5 mg oral OaD; Group V: vacuum erectile devices treatment for 15 min twice daily; Group T+V: tadalafil 5 mg oral OaD combined vacuum erectile devices treatment for 15 min twice daily, BMI: body mass index; LRP: laparoscopic radical prostatectomy; PLNES: penile length in non-erection state; PSA: prostate-specific antigen; RARP: robot-assisted radical prostatectomy; s.d.: standard deviation; OaD: once a day; IIEF-5: International Index of Erectile Function-5