TABLE 4.
Class C β-lactamases and species-specific progenitors
| Enzyme/straina | First identification | Updated identification | %b | References |
|---|---|---|---|---|
| ACC-1*c | Hafnia alvei | Hafnia paralvei | 99.7 | 321, this review |
| ACT-1*c | Enterobacter cloacae | Enterobacter asburiae | 98.4 | 322, this review |
| Aer-1 | Enterobacter aerogenes | Klebsiella aerogenes | 98.9 | 338, 363 |
| AQU-1 | Aeromonas aquariorum | Aeromonas dhakensis | 99.2 | 249, 364 |
| AsbA1 | Aeromonas sobria | Aeromonas jandaei | 94.5 | 324, this review |
| BIL-1* | Citrobacter freundii | Citrobacter portucalensis | 96.8 | 326, this review |
| BUT-1 | Buttiauxella sp. | Scandinavium goeteborgense | 99.0 | 329, 365 |
| BUT-2 | Buttiauxella agrestis | Scandinavium goeteborgense | 99.5 | 339, 365 |
| CAV-1 | Aeromonas caviae | Aeromonas allosaccharophila | 97.1 | 44, 71 |
| CFE-1* | Citrobacter freundii | Citrobacter europaeus | 99.2 | 208, this review |
| CFE-2* | Citrobacter freundii | Citrobacter werkmanii | 95.0 | 366, this review |
| CMY-1*c | Aeromonas hydrophila | Aeromonas sanarellii | 95.3 | 233, this review |
| CMY-2* | Citrobacter freundii | Citrobacter portucalensis | 98.4 | 335, this review |
| EDC-1 | Edwardsiella tarda | Edwardsiella piscicida | 99.1 | This review |
| FOX-1* | Aeromonas caviae | Aeromonas allosaccharophila | 94-98 | 71, 341 |
| LAT-1* | Citrobacter freundii | Citrobacter portucalensis | 97.4 | 345, this review |
| MIR-1*c | Enterobacter cloacae | Enterobacter roggenkampii | 99.7 | 25, 352 |
| MOX-1* | Aeromonas hydrophila | Aeromonas sanarellii | 94.5 | 72, 232 |
| MOX-2* | Aeromonas sp. | Aeromonas caviae | 98.9 | 72, 234 |
| MOX-9* | Aeromonas caviae | Aeromonas media | 98.0 | 72, 367 |
| P99 (ACT-89) | Enterobacter cloacae | Enterobacter hormaechei | 97.9 | 25, 352, this review |
| TRU-1 | Aeromonas tructi | Aeromonas enteropelogenes | 97.1 | 360, this review |
Plasmid-encoded enzymes are labeled by an asterisk.
Percentage of identity with consensus sequence.
Other plasmid-encoded types: ACC-4 (99.5% for H. paralvei); ACT-3, ACT-6, ACT-8, and ACT-10 (≥97.6% for E. asburiae); CMY-17, CMY-55, CMY-132, and CMY-161 (≥ 98.1% for A. sanarellii); MIR-4 (99.4% for E. roggenkampii). Their respective phylogenies can be found in references 32, 46, 50, and 63; and 73 and 74.