Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Immune sensing and antagonism of SARS-CoV-2 to inhibit IFN responses. Immune sensing of SARS-CoV-2 by host pattern recognition receptors activates IFN expression and secretion (left). Secreted IFNs bind to IFN receptors to trigger IFN-stimulated gene production in an autocrine or paracrine manner (right). SARS-CoV-2 proteins that can target each layer of IFN pathway are shown as red inhibition signs.
