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Rotarix fecal shedding in infants vaccinated with monovalent P2-VP8-P[8]a
| Parameter | Placebo | P2-VP8-P[8], 30 μg | P2-VP8-P[8], 60 μg | 30 μg and 60 μg, combined |
|---|---|---|---|---|
| No. (%) shedding on day 5, 7, or 9 | 17/44 (39) | 6/45 (13) | 9/46 (20) | 15/91 (17) |
| % reduction compared to placebo (95% CI) | NA | 66 (21–85) | 49 (0–75) | 57 (23–76) |
| P | 0.0087 | 0.0493 | 0.0052 |
Data were reproduced from Groome et al. (553). 95% CI, 95% confidence interval.
