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. 2022 Jul 6;35(3):e00008-21. doi: 10.1128/cmr.00008-21

TABLE 25.

Strains of influenza responsible for pandemics spanning a centurya

Period (yrs) Pandemic Strain Species of origin of HA and NA genes
1918–1923 Spanish flu H1N1 Human
1957–1958 Asian flu H2N2 Avian
1968–1969 Hong Kong flu H3N2 Avian
2009–2010 2009 A(H1N1) A(H1N1) Porcine and avian
a

HA, hemagglutinin; NA, neuraminidase.