TABLE 33.
Trade name | Valency | Components | Developer | Licensure (yr) |
---|---|---|---|---|
Infanrix | DTaP(3) | Pertussis toxin, filamentous hemagglutinin, pertactin, diphtheria toxoid, tetanus toxoid | GlaxoSmithKline | 1997 |
Daptacel | DTaP(5) | Pertussis toxin, filamentous hemagglutinin, pertactin, fimbrial types 2 and 3, diphtheria toxoid, tetanus toxoid | Sanofi Pasteur | 2002 |
GlaxoSmithKline has licensed additional formulations of the same three pertussis antigens combined with inactivated poliovirus and hepatitis B virus. Sanofi Pasteur has licensed additional formulations of the same five pertussis antigens in different combinations with inactivated poliovirus, Haemophilus influenzae type B, and hepatitis B under the names Tetraxim, Pentaxim, and Hexaxim.