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. 2022 Sep 7;13:952140. doi: 10.3389/fphys.2022.952140

TABLE 3.

HR-pQCT (Radius and Tibia) and serum parameters at baseline.

Group
Control (n = 98) Vibration (n = 99) p-value
Mean SD Mean SD
HR-pQCT (Tibia)
 Total BMD (mgHA/cm3) 257.5 49.15 253.4 48.44 0.576
 Trabecular vBMD (mgHA/cm3) 154.53 34.96 152.4 35.93 0.688
 BV/TV (%) 0.13 0.03 0.13 0.03 0.686
 Trabecular inhomogeneity (Tb.1/N.SD; mm) 0.29 0.16 0.35 0.38 0.157
 Cortical area (mm2) 96.6 14.51 92.39 15.72 0.065
 Cortical vBMD (mgHA/cm3) 795.6 60.3 806.31 64.9 0.256
 Cortical perimeter (mm) 99.49 7.38 99.86 6.7 0.728
 Cortical thickness (mm) 1.07 0.18 1.02 0.18 0.091
 Cortical porosity (%) 0.08 0.03 0.07 0.03 0.051
 Ultimate load (N) −8028.69 1,265.94 −8020.71 1,320.72 0.967
 Trabecular load vs. whole bone load (distal) 0.52 0.09 0.53 0.1 0.397
 Trabecular load vs. whole bone load (proximal) 0.32 0.08 0.33 0.09 0.32
 Trabecular Von Mises stress (MPa) 52.76 7.11 54.06 7.18 0.225
 Cortical Von Mises stress (MPa) 86.01 2.21 86.19 2.41 0.612
 Total Muscle Volume (mm3) 19,625.05 4,851.78 18,770.96 3,965.69 0.201
 MV/TV 0.55 0.15 0.57 0.13 0.453
HR-pQCT (Radius)
 Total BMD (mgHA/cm3) 295.95 67.08 295.05 59.35 0.934
 Trabecular vBMD (mgHA/cm3) 149.62 39.62 142.75 41.17 0.321
 BV/TV (%) 0.12 0.03 0.12 0.03 0.319
 Trabecular inhomogeneity (Tb.1/N.SD; mm) 0.29 0.21 0.33 0.22 0.368
 Cortical area (mm2) 48.88 8.26 48.73 7.64 0.915
 Cortical vBMD (mgHA/cm3) 847 56.1 863.29 59.37 0.101
 Cortical perimeter (mm) 68.8 10.67 66.76 5.04 0.145
 Cortical thickness (mm) 0.81 0.16 0.82 0.15 0.748
 Cortical porosity (%) 0.025 0.013 0.02 0.009 0.011
 Ultimate load (N) −2,859.75 551.01 −2901.77 541.36 0.654
 Trabecular load vs. whole bone load (distal) 0.44 0.07 0.44 0.1 0.952
 Trabecular load vs. whole bone load (proximal) 0.16 0.06 0.16 0.06 0.656
 Trabecular Von Mises stress (MPa) 42.42 6.29 43.61 7.24 0.31
 Cortical Von Mises stress (MPa) 78.92 3.81 79.99 3.55 0.092
Serum
 P1NP (µg/L) 55.77 23.87 56.17 18.39 0.897
 CTX (pmol/L) 4,141.05 2,379.15 4,332.82 1,836.07 0.527
 BAP (µg/L) 12.25 4.12 11.71 3.6 0.334
 Sclerostin (ng/ml) 0.64 0.15 0.6 0.15 0.062