Table 4. Comparison of clinical and laboratory characteristics at admission between patients with community-acquired acute kidney injury (C-AKI) and those with hospital-acquired acute kidney injury (H-AKI).
| Variables | C-AKI (n = 55) | H-AKI (n = 48) | P | ||
|---|---|---|---|---|---|
| n/median | %/IQR | n/median | %/IQR | ||
| General characteristics: | |||||
| Age (years) (mean ± SD) | 61 ± 15 | 60 ± 14 | 0.678 | ||
| Female | 18 | 32.7% | 17 | 35.4% | 0.77 |
| Male | 37 | 67.3% | 31 | 64.6% | |
| Diabetes mellitus | 28 | 50.9% | 18 | 37.5% | 0.17 |
| Hypertension | 36 | 65.5% | 24 | 50.0% | 0.11 |
| Chronic kidney disease | 7 | 12.7% | 7 | 14.6% | 0.78 |
| Respiratory support: | |||||
| Simple mask | 4 | 7.3% | 1 | 2.1% | 0.018 |
| Reservoir mask | 14 | 25.5% | 3 | 6.3% | |
| High-flow nasal canula | 2 | 3.6% | 2 | 4.2% | |
| NIV | 7 | 12.7% | 3 | 6.3% | |
| IV | 28 | 50.9% | 39 | 81.3% | |
| AKI characteristics: | |||||
| AKIN 1 | 10 | 18.2% | 6 | 12.5% | 0.32 |
| AKIN 2 | 21 | 38.2% | 14 | 29.2% | |
| AKIN 3 | 24 | 43.6% | 28 | 58.3% | |
| Hemodialysis | 7 | 12.7% | 4 | 8.3% | 0.47 |
| Recovered kidney function | 19 | 34.5% | 18 | 37.5% | 0.75 |
| Laboratory characteristics: | |||||
| Hemoglobin (g/dl) | 12.5 | (10.4-14.1) | 13.8 | (12.5-14.8) | 0.027 |
| Total leucocytes (/μl) (x1000) | 13.9 | (9.8-20.9) | 10.9 | (7.9-15.6) | 0.037 |
| Total lymphocytes (/μl) | 857 | (488-1,256) | 961 | (595-1,382) | 0.571 |
| Platelets (/μl) (x1000) | 250 | (221-318) | 253 | (188-311) | 0.999 |
| Serum creatinine (mg/dl)* | 1.8 | (1.3-2.8) | 1.4 | (1.3-2.1) | 0.256 |
| C-reactive protein (mg/dl) | 120 | (48-192) | 96 | (48-192) | 0.173 |
| Ferritin (ng/dl) | 854 | (453-1,000) | 648 | (361-964) | 0.009 |
| D-dimer (ng/dl) | 1627 | (755-3,970) | 847 | (390-2,090) | 0.020 |
| PaO2/FiO2 at admission | 140 | (102-244) | 142 | (100-236) | 0.875 |
| Index CT severity | 24 | (21-25) | 20 | (15-24) | 0.003 |
| Use of norepinephrine | 28 | 50.9 | 30 | 62.5 | 0.320 |
IQR = interquartile range; SD = standard deviation; NIV = noninvasive ventilation; IV = invasive ventilation; AKIN = acute kidney injury network. PaO2 = partial pressure of oxygen; FiO2 = fraction of inspired oxygen. *Serum creatinine at the time of AKI diagnosis.