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. 2022 Sep 21;17(9):e0274397. doi: 10.1371/journal.pone.0274397

Fig 3. Stress conditions trigger binding of BvrR discriminating according to function.

Fig 3

A. Distribution of the total number of significant signals according to the function of the closest gene and tested conditions shows a higher number of genes as BvrR putative targets under stress conditions and that targeting is selective according to function. Binding sites located close to rRNA genes were excluded from the analysis. Orange = Rich conditions. Blue = Stress conditions. B. Proportional distribution of BvrR binding sites according to the function of the closest gene in stress conditions. C. Venn Diagram generated with an online tool (https://bioinformatics.psb.ugent.be/webtools/Venn/) and illustrating the relationship between the BvrR target genes inferred in this study and the differentially expressed genes identified in previous proteomics [15] and transcriptomics [16] studies performed with the B. abortus 2308 WT and bvrR::Tn5 strains.