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. 2022 Sep 21;17(9):e0274177. doi: 10.1371/journal.pone.0274177

Table 2. Summary of subgroup analyses of online MBIs effect on mental health outcomes at post-intervention (including outliers).

Outcome Measure Covariate Subgroup Number of Studies Effect Size Heterogeneity p-value of Difference between Subgroups
Hedges’ g 95% CI Z p-value I 2 p-value
Depression Study region Asia 2 -0.28 -0.59, 0.03 1.75 0.08 0% 0.91 0.76
Non-Asia 3 -0.34 -0.55, -0.12 3.01 0.003 0% 0.57
Delivery method Videoconferencing 2 -0.35 -0.62, -0.08 2.52 0.01 0% 0.86 0.75
Non-videoconferencing 3 -0.29 -0.53, -0.05 2.40 0.02 0% 0.57
Guidance With 3 -0.32 -0.54, 0.10 2.86 0.004 0% 0.92 0.95
Without 2 -0.31 -0.63, 0.01 1.87 0.06 7% 0.30
Anxiety Study region Asia 3 -0.08 -0.30, 0.14 0.72 0.47 0% 0.73 0.03a
Non-Asia 3 -0.42 -0.64, -0.20 3.77 < 0.001 0% 0.47
Control type Active 2 -0.04 -0.28, 0.19 0.37 0.71 0% 0.82 0.02a
Inactive 4 -0.40 -0.61, -0.20 3.87 < 0.001 0% 0.64
Delivery method Videoconferencing 2 -0.46 -0.74, -0.19 3.34 < 0.001 0% 0.48 0.06
Non-videoconferencing 4 -0.15 -0.34, 0.04 1.55 0.12 0% 0.42
Guidance With 3 -0.28 -0.62, 0.05 1.64 0.10 53% 0.12 0.69
Without 3 -0.20 -0.43, 0.03 1.72 0.09 5% 0.35
Stress Study region Asia 3 -0.25 -0.47, -0.03 2.24 0.02 0% 0.49 0.08
Non-Asia 2 -1.20 -2.24, -0.16 2.25 0.02 88% 0.00
Population type General population 2 -0.91 -2.52, 0.69 1.12 0.26 96% < 0.001 0.61
Non-general population 3 -0.50 -0.74, -0.25 3.98 < 0.001 0% 0.48
MBI type MBSR 2 -1.05 -2.39, 0.28 1.54 0.12 93% < 0.001 0.34
MBCT 3 -0.37 -0.75, 0.00 1.94 0.05 60% 0.08
Control type Active 2 -0.24 -0.51, 0.03 1.72 0.09 22% 0.26 0.09
Inactive 3 -0.92 -1.66, -0.18 2.43 0.02 84% 0.002
Delivery method Videoconferencing 3 -0.81 -1.64, 0.01 1.93 0.05 87% < 0.001 0.40
Non-videoconferencing 2 -0.39 -0.95, 0.17 1.35 0.18 80% 0.03
Guidance With 3 -0.81 -1.64, 0.01 1.93 0.05 87% < 0.001 0.40
Without 2 -0.39 -0.95, 0.17 1.35 0.18 80% 0.03

a p < 0.05

CI, confidence interval; MBCT, Mindfulness-Based Cognitive Therapy; MBI, mindfulness-based intervention; MBSR, Mindfulness-Based Stress Reduction.