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. 2022 Sep 21;17(9):e0272030. doi: 10.1371/journal.pone.0272030

Table 1. Preoperative characteristics.

Control (n = 17) Virtual Reality (n = 17) Standardized Difference*
Age, years 50.1±11.1 48.7±19.0 -0.09
Female sex 8 (47.1) 5 (29.4) -0.37
BMI, kg/m2 28.7±5.2 28.1±4.8 -0.12
Diabetes 4 (23.5) 2 (11.8) -0.31
Hypertension 6 (35.3) 9 (52.9) 0.36
Dyslipidemia 6 (35.3) 5 (29.4) -0.13
Obesity 7 (41.2) 3 (17.6) -0.53
COPD 4 (23.5) 3 (17.6) -0.15
Depression 6 (35.3) 3 (17.6) -0.41
Anxiety 3 (17.6) 2 (11.8) -0.17
Previous Use of VR
Never, 13 (76.5) 10 (58.8) 0.74
Once 2 (11.8) 3 (17.6)
A few times 1 (5.9) 4 (23.5)
Many times 0 (0) 1 (5.9)
Procedure Type a
Carpal tunnel 4 (23.5) 4 (23.5) 0.00
Dupuytren’s contracture 1 (5.9) 2 (11.8) 0.21
Tendon/ligament repair 5 (29.4) 3 (17.6) -0.28
Ganglion removal 3 (17.6) 3 (17.6) 0.00
Ulnar neurolysis/decompression 2 (11.8) 4 (23.5) 0.31
Mass/cyst excision 3 (17.6) 1 (5.9) -0.37
Reduction and/or internal fixation 2 (11.8) 3 (17.6) 0.17
Other 4 (23.5) 2 (11.8) -0.31
Surgery length, minutes 27.0 (16.5–45.5) 19.0 (12.5–51.0) -1.17
Regional Anesthetic
Supraclavicular 4 (23.5) 7 (41.2) 0.38
Infraclavicular 11 (64.7) 8 (47.1) -0.36
None/data missing 2 (11.8) 2 (11.8) -0.35
Bupivacaine, mg 100 (75–100) 100 (67.5–100) -0.21
Mepivacaine, mg 240 (200–300) 200 (200–200) -1.17
Midazolam (preoperative/ intraoperative) 17 (100) 13 (76.5) -0.78

Values are presented as n (%), mean ±SD, or median (Q1-Q3) depending on variable type and distribution.

a Multiple bookings per case are possible.

b Calculated as the difference in means or proportions divided by the pooled standard deviation. * Significant imbalance is defined as an absolute standardized difference > 0.67.