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. 2022 Sep 21;23(1):45–55. doi: 10.1016/S1473-3099(22)00578-3

Table 2.

Vaccination status of presumed omicron BA.2 cases and controls stratified by SARS-CoV-2 primary infection (pre-omicron or omicron BA.1)

All infections analysis
Symptomatic infections analysis*
Cases (n=37 732) Controls (n=73 507) Cases (n=23 371) Controls (n=30 542)
Pre-omicron primary infection
Overall 2521 (6·7%) 7360 (10·0%) 1495 (6·4%) 2643 (8·7%)
Non-vaccinated 109 (0·3%) 265 (0·4%) 57 (0·2%) 41 (0·1%)
One vaccine dose 342 (0·9%) 729 (1·0%) 214 (0·9%) 285 (0·9%)
Primary infection, first dose 340 (0·9%) 722 (1·0%) 212 (0·9%) 283 (0·9%)
First dose, primary infection 2 (<0·1%) 7 (<0·1%) 2 (<0·1%) 2 (<0·1%)
Two vaccine doses 897 (2·4%) 2665 (3·6%) 540 (2·3%) 987 (3·2%)
Primary infection, two doses 815 (2·2%) 2376 (3·2%) 486 (2·1%) 860 (2·8%)
First dose, primary infection, second dose 39 (0·1%) 107 (0·1%) 24 (0·1%) 56 (0·2%)
Two doses, primary infection 43 (0·1%) 182 (0·2%) 30 (0·1%) 71 (0·2%)
Three vaccine doses 1173 (3·1%) 3701 (5·0%) 684 (2·9%) 1330 (4·4%)
Primary infection, three doses 1028 (2·7%) 3177 (4·3%) 594 (2·5%) 1118 (3·7%)
First dose, primary infection, second and third doses 83 (0·2%) 271 (0·4%) 52 (0·2%) 99 (0·3%)
Two doses, primary infection, third dose 62 (0·2%) 253 (0·3%) 38 (0·2%) 113 (0·4%)
Omicron BA.1 primary infection
Overall 659 (1·7%) 12315 (16·8%) 330 (1·4%) 5600 (18·3%)
Non-vaccinated 125 (0·3%) 727 (1·0%) 43 (0·2%) 119 (0·4%)
One vaccine dose 9 (<0·1%) 109 (0·1%) 3 (<0·1%) 33 (<0·1%)
Primary infection, first dose 1 (<0·1%) 6 (<0·1%) 1 (<0·1%) 2 (<0·1%)
First dose, primary infection 8 (<0·1%) 103 (<0·1%) 2 (<0·1%) 31 (<0·1%)
Two vaccine doses 262 (0·7%) 5322 (7·2%) 147 (0·6%) 2519 (8·2%)
Two doses, primary infection 262 (0·7%) 5314 (7·2%) 147 (0·6%) 2517 (8·2%)
First dose, primary infection, second dose 0 8 (<0·1%) 0 2 (<0·1%)
Three vaccine doses 263 (0·7%) 6157 (8·4%) 137 (0·6%) 2929 (9·6%)
Three doses, primary infection 243 (0·6%) 5679 (7·7%) 124 (0·5%) 2716 (8·9%)
Two doses, primary infection, third dose 20 (0·1%) 478 (0·7%) 13 (0·1%) 213 (0·7%)
No previous SARS-CoV-2 infection
Overall 34 552 (91·6%) 53 832 (73·2%) 21 546 (92·2%) 22 299 (73·0%)
Non-vaccinated 672 (1·8%) 1043 (1·4%) 343 (1·5%) 125 (0·4%)
One vaccine dose 136 (0·4%) 193 (0·3%) 68 (0·3%) 45 (0·1%)
Two vaccine doses 6717 (17·8%) 8939 (12·2%) 4387 (18·8%) 3839 (12·6%)
Three vaccine doses 27 027 (71·6%) 43 657 (59·4%) 16 748 (71·7%) 18 290 (59·9%)
*

Including only participants who had symptoms at the time of specimen collection according to the indication for testing.