Figure 1.
Incidence rate of AAA hospitalizations per 1,000 for CKD measures (A: eGFR, B: ACR), adjusted for age, gender, race, and centre in the Atherosclerosis Risk in Community Study. The demographically adjusted hazard ratio (HR) for AAA development was 4.44 (95% CI 1.58–12.49) for eGFR <30 mL/min/1.73 m2, 3.29 (1.89–5.72) for 30–44 mL/min/1.73 m2, 2.03 (1.29–3.19) for 45–59 mL/min/1.73 m2, and 1.62 (1.11–2.35) for 60–74 mL/min/1.73 m2 compared with eGFR ≥90 mL/min/1.73 m2. Furthermore, the demographically adjusted HR was 2.49 (1.28–4.87) for ACR ≥300 mg/g, 1.99 (1.40–2.83) for 30–299 mg/g, and 1.46 (1.08–1.97) for 10–29 mg/g compared with ACR <10 mg/g. These associations were generally similar after accounting for additional covariates or after stratifying by subgroups. Adapted with permission from Matsushita et al.9