FIG. 2.

Topology diagram of acetate kinase. Secondary structures conserved in the ASKHA family (the duplicated βββαβαβα core) are rendered gray, and the inserts are shown in white. In standard nomenclature, the βββαβαβα subdomains are denoted IA (left) and IIA (right). In acetate kinase, the core β strands in domain IA are numbered 1 to 5, whereas those in domain IIA are numbered 1′ to 5′.