Extended Data Fig. 5. Differences in functional category composition, metabolic gene content changes and differential contribution of gene fusion originations vs non-fusion originations to each functional category in Opisthokonta.

(A) Relative and (B) absolute counts of functional categories in the opisthokont species from euk_db (Supplementary Tables 7 and 8, respectively). (C) Gains and losses of metabolic genes (KEGG orthology groups) in the Opisthokonta nodes preceding H. sapiens and (D) in the Opisthokonta nodes preceding N. crassa (Supplementary Table 9). (E) Differential representation of functional categories among fusion originations vs non-fusion originations in the Opisthokonta nodes preceding H. sapiens and (F) in the Opisthokonta nodes preceding N. crassa (Supplementary Table 10).