Table 2.
Characteristics of the hypertensive population according to tertiles of iron status in men (n = 718) (Data are expressed as the means ± SDs for normally distributed variables or as the median [interquartile range] for non-normally distributed variables, or counts (percentages) for categorical variables)
| Characteristics | Tertiles of SF | Tertiles of Hb | ||||||
|---|---|---|---|---|---|---|---|---|
| T1 | T2 | T3 | P for trenda | T1 | T2 | T3 | P for trenda | |
| Age (years) | 57.09 ± 9.86 | 53.18 ± 9.91 | 52.89 ± 9.34 | < 0.001 | 57.77 ± 10.24 | 54.01 ± 9.38 | 51.60 ± 9.15 | < 0.001 |
| Marital status, n (%) | 0.602 | 0.509 | ||||||
| Married | 229 (96.6) | 235 (96.3) | 231 (97.5) | 218 (98.6) | 246 (94.6) | 231 (97.5) | ||
| Unmarried | 8 (3.4) | 9 (3.7) | 6 (2.5) | 3 (1.4) | 14 (5.4) | 6 (2.5) | ||
| Education level, n (%) | 0.004 | 0.829 | ||||||
| Primary school or below | 29 (12.2) | 23 (9.4) | 9 (3.8) | 20 (9.0) | 21 (8.1) | 20 (8.4) | ||
| High school | 127 (53.6) | 135 (55.3) | 153 (64.6) | 127 (57.5) | 149 (57.3) | 139 (58.6) | ||
| College or above | 81 (34.2) | 86 (35.2) | 75 (31.6) | 74 (33.5) | 90 (34.6) | 78 (32.9) | ||
| Current drinker, n (%) | 0.008 | 0.001 | ||||||
| No | 140 (59.1) | 131 (53.7) | 111 (46.8) | 141 (63.8) | 133 (51.2) | 108 (45.6) | ||
| Yes | 97 (40.9) | 113 (46.3) | 126 (53.2) | 80 (36.2) | 127 (48.8) | 129 (54.4) | ||
| Physical activity, n (%) | 0.055 | 0.017 | ||||||
| No | 67 (28.3) | 100 (41.0) | 87 (36.7) | 65 (29.4) | 94 (36.2) | 95 (40.1) | ||
| Yes | 170 (71.7) | 144 (59.0) | 150 (63.3) | 156 (70.6) | 166 (63.8) | 142 (59.9) | ||
| BMI (kg/m2) | 25.40 ± 2.95 | 26.16 ± 3.23 | 26.05 ± 3.17 | 0.050 | 24.93 ± 2.99 | 26.16 ± 3.21 | 26.44 ± 2.98 | < 0.001 |
| TG (mmol/L) | 1.43 [0.95, 2.01] | 1.66 [1.14, 2.36] | 1.84 [1.46, 2.70] | < 0.001 | 1.41 [0.96, 1.96] | 1.73 [1.20, 2.33] | 1.81 [1.26, 2.56] | < 0.001 |
| LDL-C (mmol/L) | 3.20 ± 0.74 | 3.25 ± 0.75 | 3.17 ± 0.74 | 0.626 | 3.07 ± 0.65 | 3.24 ± 0.81 | 3.30 ± 0.74 | 0.002 |
| hs-CRP (mg/L) | 1.20 [0.70, 2.10] | 1.30 [0.70, 2.30] | 1.40 [0.80, 2.90] | 0.006 | 1.30 [0.70, 2.36] | 1.40 [0.80, 2.52] | 1.20 [0.70, 2.20] | 0.062 |
| SF (ng/mL) | 117.01 [85.57, 144.30] | 215.12 [190.69, 243.35] | 386.62 [325.71, 484.93] | < 0.001 | 210.33 [128.45, 327.44] | 207.32 [140.01, 312.45] | 234.09 [165.02, 329.58] | 0.010 |
| Hb (g/L) | 143.59 ± 11.96 | 146.34 ± 11.47 | 145.57 ± 12.01 | 0.133 | 131.65 ± 6.91 | 145.14 ± 3.09 | 157.84 ± 6.29 | < 0.001 |
| ASCVD risk score (%) | 6.50 [4.40, 9.00] | 4.95 [2.80, 7.70] | 5.60 [3.50, 8.00] | 0.242 | 6.70 [4.30, 9.40] | 5.45 [3.58, 7.90] | 5.20 [3.00, 7.60] | 0.005 |
ASCVD, atherosclerotic cardiovascular disease; BMI, body mass index; Hb, haemoglobin; hs-CRP, high sensitivity C-reactive protein; LDL-C, low-density lipoprotein cholesterol; SF, serum ferritin; T, tertile; TG, triglyceride
aLinear trends were tested using linear regression for continuous variables (with the median levels of SF or Hb as a continuous variable included in the regression models), and χ2 with linear-by-linear association test for categorical variables