Table 2.

Factors that predispose to, or protect against, the development of hypophosphatemia

Predisposing factors for the development of hypophosphatemia

Dose and number of doses of intravenous iron

Severity of iron deficiency, expressed by lower ferritin

Pre-existing low serum phosphate concentration

Vitamin D deficiency

Hyperparathyroidism

Bariatric surgery: Roux-Y gastric bypass

Malabsorption

Malnourishment or relatively low body weight

Increasing age

Renal transplant

Drugs for osteoporosis: denosumab and bisphosphonates

Black race

Factors for protection against the development of hypophosphatemia

Increasing renal insufficiency