Fig. 1. Frequency of variant sharing across species.

a Number of human (1000 genomes) SNPs that have a SNP at the orthologous location in each other species. Counts are broken down into where the SNPs have the same alleles across species (same site and alleles) or simply coincide, i.e. irrespective of allele change. The inset shows the number of orthologous SNPs expected in larger cohorts when extrapolating the curves. b The number of human variants overlapping a variant found in one or more other species with a matching allele change. The vertical bars indicate the number of human orthologues found across the species indicated by the dots below. The horizontal bars indicate the total number of orthologues in that species. The data underlying this plot can be found in Supplementary Data 1.