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. 2022 Sep 8;12:980157. doi: 10.3389/fcimb.2022.980157

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Copyright © 2022 Zhang, Yun, Yue, Du and Liang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution of the microbiota composition and biomarkers. (A) Venn diagram of the taxonomic distribution, the percentage under OTU numbers represent reads percentages of all sequencing data. (B-C) The result of linear discriminant analysis integrated with effect size (LEfSe). Microbial marker taxa with significant abundance differences among HO, PAP, HARD and SOFT (B) and between HARD and SOFT (C) (LDA > 3.5, p < 0.05).