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. 2022 Sep 8;10:939119. doi: 10.3389/fped.2022.939119

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Copyright © 2022 Zhong, Song, Liu, Sun, Zhang, Chen, Diao, Li, Li, Shu, Wei, Zhu, Wang and Qin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Association between MTHFR genetic variants and risk of CHD. CHD, congenital heart disease; CI, confidence interval; OR, odds ratio; MTHFR, Methylenetetrahydrofolate reductase; FDR, false discovery rate. ^†Adjusted for gender, maternal education status, residence location, adverse pregnancy history (induced abortion or labor, fetal death or stillbirth, neonatal death, hypertension of pregnancy, gestational diabetes mellitus), family history (consanguineous marriages), maternal lifestyle before this pregnancy, harmful chemical exposure history in this pregnancy.