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. 2022 Sep 8;10:946932. doi: 10.3389/fped.2022.946932

Table 2.

Perinatal parameters of control, FGR, term FGR, and preterm FGR neonates.

Variable Control FGR P-value Term FGR Preterm FGR P-value
N 118 74 48 26
T at birth (°C) 36.3 (36.1–36.6) 36.10 (35.90–36.40) 0.007 36.2 (36.0–36.4) 36.0 (35.8–36.5) 0.0767
APGAR 1': <5* 0 1 0.04 0 4 0.02
5–7 (%) 0 4 0 12
8–10 (%) 100 95 100 85
APGAR 5':8–10* 100 100 100 100
Blood group: O* 39 36 0.73 35 38 0.80
Neonatal WBC (x109/L) 13.2 (11.4–15.2) 11.4 (9.54–13.5) <0.001 12.8 (10.7–14.6) 9.57 (7.02–11.1) 0.38
Neonatal Hb (g/dl) 15.15 (14.4–16.05) 16.10 (15.10–17.00) <0.001 16.1 (15.1–17.5) 16.2 (15.0–16.9) 0.54
Neonatal Hct (%) 45.1 (42.2–47.75) 48.00 (45.00–50.80) <0.001 48.0 (45.0–53.0) 48.0 (44.7–50.0) 0.58
Neonatal PLT (x109/L) 251.0 (207.5–296.0) 243.0 (187.0–283.0) 0.16 248.0 (187.0–291.0) 233.5 (192.0–277.0) 0.47
Neonatal MPV (fL) 9.8 (8.4–10.5) 9.70 (8.00–10.40) 0.59 9.9 (8.2–10.5) 8.8 (7.6–10.0) 0.11
Aspirin: no* 92 80 0.04 81 77 <0.001
<7 days before labor 2 8 0 23
>7 days before labor 7 12 19 0
LMWH* 8 14 0.27 8 23 0.08
Anesthesia: epidural* 75 80 0.49 75 88 0.17
General 1 5 0.05 4 8 0.52
Pethidine 4 1 0.27 2 0 0.45
Ampicillin peripartum* 10 7 0.42 8 4 0.46
Hypothyroidism* 14 22 0.16 12 38 0.01
Smoking* N/A 23 21 27 0.55
PIH/preeclampsia* N/A 9 8 12 0.65
Thrombophilia* N/A 7 8 4 0.49
HC (cm) N/A 32.70 (31.50–34.00) 33.6 (32.5–34.3) 31.2 (29.7–32.0) <0.001
AC (cm) N/A 28.25 (26.10–29.50) 28.9 (27.5–30.5) 26.0 (25.0–27.5) <0.001
CI N/A 1.30 (1.24–1.51) 1.3 (1.2–1.3) 1.6 (1.5–1.8) <0.001
HC/AC N/A 1.15 (1.11–1.21) 1.1 (1.1–1.2) 1.2 (1.1–1.2) 0.26

Arithmetic data are shown as median values (25–75th pctl). *Categorical characteristics are presented as percentages. Bold values indicate statistical significance. T, temperature; LMWH, low molecular weight heparin; PIH, pregnancy-induced hypertension; HC, head circumference; AC, abdominal circumference; CI, cephalization index; N/A, not available.