TABLE 2.
Detailed demographic and clinical information of PD patients.
| PD (n = 89) | PD-N (n = 63) | PDD (n = 26) | P | |
| Age, years | 59.85 ± 10.54 | 58.19 ± 10.70 | 63.88 ± 9.14 | 0.020 |
| Male (n, %) | 61 (68.5) | 42 (66.7) | 19 (73.1) | 0.554 |
| Education (n, %) | < 0.001 | |||
| Junior high school and below | 38 (42.7) | 19 (30.2) | 19 (73.1) | |
| Senior high school | 30 (33.7) | 24 (38.1) | 6 (23.1) | |
| College and above | 21 (23.6) | 20 (31.7) | 1 (3.8) | |
| BMI (kg/m2) | 24.42 ± 3.40 | 24.25 ± 3.41 | 24.82 ± 3.40 | 0.483 |
| Hypertension (n, %) | 24 (27.0) | 15 (23.8) | 9 (34.6) | 0.296 |
| Tremor | 42 (47.2) | 31 (49.2) | 11 (42.3) | 0.553 |
| Bradykinesia | 79 (88.8) | 53 (87.3) | 24 (92.3) | 0.717 |
| Rigidity | 79 (89.8) | 58 (93.5) | 21 (80.8) | 0.117 |
| RBD | 37 (41.6) | 29 (46.0) | 8 (30.8) | 0.184 |
| Disease duration, years | 3.0 (1.5–5.0) | 2.0 (1.5–5.0) | 3.25 (2.0–5.25) | 0.239 |
| H&Y stage | 2.20 ± 0.79 | 2.10 ± 0.71 | 2.44 ± 0.95 | 0.068 |
| UPDRS | 45.0 (30.0–75.5) | 41.0 (29.0–62.5) | 68.5 (38.0–78.75) | 0.034 |
| UPDRS part III | 30.51 ± 15.95 | 28.42 ± 15.95 | 35.32 ± 14.29 | 0.065 |
| NMSS | 27.0 (11.0–47.25) | 22.0 (9.75, 44.25) | 37.5 (17.75–59.0) | 0.144 |
| PDQ-39 | 23.0 (14.0–46.0) | 21.5 (14.0–41.5) | 30.0 (11.0–58.0) | 0.212 |
| HAMD | 6.0 (3.0–11.0) | 6.0 (3.0–10.0) | 5.0 (3.25–13.25) | 0.886 |
| MoCA | 23.11 ± 4.27 | 25.24 ± 2.63 | 17.96 ± 2.85 | < 0.001 |
| OH (n, %) | 21 (23.6) | 10 (15.9) | 11 (42.3) | 0.008 |
| OH subtypes (n, %) | ||||
| Initial OH | 11 (12.3) | 4 (6.3) | 7 (26.9) | |
| Classic OH | 7 (7.9) | 5 (7.9) | 2 (7.7) | |
| Delayed OH | 3 (3.4) | 1 (1.6) | 2 (7.7) |
Values are expressed as mean ± SD, median (IQR) or n (%). PD-N, patients with Parkinson’s disease without dementia; PDD, patients with Parkinson’s disease with dementia; BMI, body mass index; RBD, rapid eye movement sleep behavior disorder; H&Y, Hoehn and Yahr Scale; UPDRS, unified Parkinson’s disease rating scale; NMSS, non-Motor Symptoms Scale; PDQ-39, 39-item Parkinson’s disease Questionnaire; HAMD, Hamilton Depression Rating Scale; MoCA, Montreal Cognitive Assessment; OH, orthostatic hypotension.