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. 2022 Sep 8;13:900273. doi: 10.3389/fimmu.2022.900273

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Copyright © 2022 Han, Ye, Huang, Li, Liu, Meng and Song

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The correlation between IL-17B expression and immunomodulators including immunostimulators (A), immunoinhibitors (B), and MHC molecules (C). The scatter plots represent the top four strongest correlations in each heatmap (D–F). The correlation between IL-17A–F expression and immunotherapeutic biomarker (TMB and MSI). The red radar charts represent the association between TMB (G) and IL-17A, IL-17B, IL-17C, IL-17D, IL-25, and IL-17F. The green radar charts represent MSI (H) and IL-17A, IL-17B, IL-17C, IL-17D, IL-25, and IL-17F. (∗∗∗p < 0.001; ∗∗p < 0.01; ∗p < 0.05.).